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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a9bd9cc2c74503ec3b95e1a431d47c0510e592e249c7514f64a5a8c20d52f18' 
  AND token = 'hp7a0TcgLjRF5es/wBsDbsg22HzQ6OVlok4AbUUy2lQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}