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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a3290de3e87ee688cdceef8930bf1dbfbc2cb2aa2dd899b99bf746a98d1b8aa' 
  AND token = 'Z009xFS1uW74nwZKQNBiqVUOW0qS8AHKzWiauHIY5aM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}