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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e3f742a893c5d3d3b4ce7bcc2b772f14fb1d017eb3f1cfb253c579767ddd6df' 
  AND token = 'EwxM2BA69/xUZJ4zQ/zWcHvyOp+C0A18TmutDrnbqiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}