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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2539440042ae5a9eb1961702598f9f694d2f7d3db44fccc5ccb0591bf3007579' 
  AND token = '1cHRgIqKepubAm1FPD4pI5lQKM90kIGBuKYjAgg9R7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}