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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b27bf0ec0d55a0c7222f302366215d2344d02e354534303b0d583df2db7173a6' 
  AND token = '8CntiBSOChA4qH+qt88ZuHdEOoA+K/3aLptoQIvcJIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}