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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21d0892af820737ee799dfeabc91027639fa44cc36874dd40953d4b068ecec56' 
  AND token = '/H03nwxGItXrjLhyaZLvvsYwnpJU//CX6oLrt32Meos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}