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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03f94ce7763b77e652528b9bc47d125ae425c279d2ff3108e02c590c38cb0a64' 
  AND token = 'F6ySt3JqK+Usd/p2ilcsdyDsAsV6ZFCDHHM95yWQyI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}