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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6c2c9203efa91b3f0f3d65960a9c0462b83acb5cfcd9c37ccebe10c99208b65' 
  AND token = '0XS55QyA+wqCDL2SmtXIjRNsZmRVj2NacwxadEN0tBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}