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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '366c23d9926f3b2f78a39443d709f2e0354c2ab8bd9d29462129740acacf6b02' 
  AND token = 'O+B1kaXHbUBXoxmgFK3G3R/w2ZHQRPCkk4a0MtHU2Us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}