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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '814e2a7299b876c6a3607c3ad3db336e45771007a04c5b140b096f8fee62972f' 
  AND token = 'wbyAjDTp4E0xhrZZH58x+4RQQVAM5+/cs2P7P09nriQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}