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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3a27911da27a11d341af476954e686799f09a8229e3f2d3af44f2f679a3202f' 
  AND token = 'IDuS+Xbt12MX/T/Gx7hABmSNY8s6/YqH6f/LyatSI/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}