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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5499c8a90e47cceba881d349b2296ea3de95271982ef1f1c39380ad757f65017' 
  AND token = '+4Vp1K8hJLEgKnyV/sjE1sltDE26XW79OfyQMGtskfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}