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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42fed7323b7baaf2ff533826b8fcee0e5b7f1998d4e83327a879f7002ef019c7' 
  AND token = '2phL2DClWWn2c3ZuMboZ2nHV8UxpzJKbQh9XqTJz6oE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}