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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3231a527d7b7a08f0f086b3bcdf3732b10fdaa9877de5c3799c8465fcfa2feb2' 
  AND token = 'GR/4fyrlDKoNVj+7t3C6ef5WICE4bMZD3xrVxOKUwWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}