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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e0ae0e21c4ef39e53d4e0cead4bd0ae9cddfeda50a6f7f1470082bcff484560' 
  AND token = 'gdAHVYj0K1FtJU2SkGpe89z1ohLxvJtbY2n7Iw/1vQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}