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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d25f9a4291353ea06f379209cf7bf5e4d862efa0adbfdbf81f50d14bdf44146' 
  AND token = 'BHMLogfzXsdayu8H+fsI3FYMrmptoCjDIwJELv0cepM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}