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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28f8d2aff1b4dd0dab945a1544c247d95fb0d1d8b3ac70e9017a1657825ad318' 
  AND token = 'csEpMpnqMULU3kb9P7zv0+215yYm1+W4D9ZQdoSVBFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}