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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '016454d1a2f3a3889bbfb2082b3cf11c92c98347c673ab00ced8e85f01851f00' 
  AND token = 'MMTSPX0lIdZZBU67fc434T745sw9tK0vodQRUHHHEU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}