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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40dc22ea04b654493f28ad675301ecbfb97e377627a11e9513cc98aa20d56a3d' 
  AND token = '+m/Gr2saQmoa1VuL/P5AGneFQQMW1HPZvHGfeJ5Vvtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}