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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '450858b0cabf96e6df434eea0e8410d5f646ee97ca7b9ec4e519e264e70e5f22' 
  AND token = 'ScAqSsVAbFDOH/22SXURlLMH2ND9hhcm/ZNVfC5l1Ak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}