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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40e789507153d103fe06d21c9dbdd3fa0f3d976b33908c2a54e7c021eb6ec841' 
  AND token = 'z2gSB9KLtU+sR5fy2gt6g6XOe4P5nZUNgcxvP+4Abxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}