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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '354c37d4e07edb7dd623e0c0d7d0c2e04b316e8fae408c038edc3d4fd4631bdb' 
  AND token = 'lY++8G4a5ZHGwL9GCwCr7NIqN52VG/EQkPF6R12b1u8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}