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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4d6556c24cd7dcdc99d16ec99ed03453cbd8a3c7969a19be80c31123ef8e9db' 
  AND token = 'VPxpDXRZ7lXkMQBwDAM/Dw7orQI18cV1qIlAInn43ps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}