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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e26250f8897e58eb98b8f92e22e09243d76cebd470b59da44958e87f6c91371' 
  AND token = 'EVprbIR9DSgI0443mM/8B5D8A60rMcTKpDqoROz2OWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}