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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b34fb9deaa7bfbba88f16bc85e03889c5ffd744d559b4b9f0505e726c3320642' 
  AND token = 'cUKD9ZV2jXNKy4AAHrAxceVzQohd5sWOoYFw5FjAvKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}