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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22860bfa167a87dff32533e909a976e47fd0d78b052ff0f74100a54e6683848b' 
  AND token = '0uxzuqwN2/O81xY75Oc5mu3IeiVYqjppVioUNek066w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}