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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd17523468ad7930dc2cd791f35079fc64b20c8639f854492b58cb0d2c5f3f2de' 
  AND token = 'h+5Q7hp7wC69znNXO+eMCnVWtjIA20rekWouaT7aD/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}