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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c65976c4323e210bc04c48b34fbc710b5cfcf210f253c1704f3da7259a571b4' 
  AND token = 'eSnv6YdzV55Ke8i3vcvoErDvaa+/b+HB+TLM2koYqdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}