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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d87f3397b74c56c79d0bea0f74f71a6e5ebf5a30dc4490257d0b6108866d22e' 
  AND token = 'PrLyLlcT8w5oHE8uE6gzVpw/PefpAiQ8nZ32Zp9h45c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}