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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f269cc391a252c298c9b951697530e48b1db7b08e46e227d7196e39f83ae4928' 
  AND token = '+1QyuNMrr9Qjzm9FhbcqpFOHPpYIepnl7/G6LcYh/Zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}