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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0f8665c92f159c385e513e0101719860ffa062e004f4638f8c3b1023c55c3cc' 
  AND token = 'lPzgZ99U8bpY2Of982uhThvHg5pHKgPujMTbf1LU3Yk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}