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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c2faa8909237a600b86ae76a374bbd6696e366bb8c9acf2d724040462d32a1d' 
  AND token = '/8YzGVZZLKN+YmXfmg8ZVxhBcyxeJYqLkxPTdRDe02M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}