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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67ab7184a586388d51b605a3abdc57da08818d2c87842c98e04effd4f3ef310d' 
  AND token = 's5hor2Z5ecu8c1GGphGzD4L6n1Q2xtEgILybFQ+q2BY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}