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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3626683e1a1790a74056877721f4f266041c3de234ba4baf2873a32b429eb7d' 
  AND token = 'RunjRFiM0Y1s+ZloGj+PzGFCAjJwYf26LH2Dtta5zHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}