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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75ee99b024fc5ff8770d41978799ffda7951078ad139f5ba4cb0bb4ffd1451cc' 
  AND token = '6erP4n+Gcjl04+YpGJlHKj8vNi94V/MZ1//lXiCdTOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}