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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a5e64341f40e66616ebb9d6ee1e644d8c8a7218660fbef581498f0d0aed79b7' 
  AND token = 'YwIrJD7m5e+KXNiHb41m/JvldX0DUUvtGpAQu66S2gE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}