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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64df33fb23cc9435479f3030facd906a7cb1e223410f8677125980c08a24ab3f' 
  AND token = 'oExUi0dBz4kjz+WFhQHCNU7WG2YaytZx460tk4YiA4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}