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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f44d92d0d74a6abb53575a212e3b43636b0e22b3d7cea94841cda9548beb06cb' 
  AND token = 'yjYJTG61l+YJ6xjrE7fP8a1QEItFf1rHQFPeHjhrSG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}