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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c550fd87bd11d1cf8992cb27b57782d3a426efeb17b43cba28f4f38d3844b5b9' 
  AND token = 'WeXf2u0zag7ZKFWkQ7LYr8NISzOH+IlfTkhsQRpf/LY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}