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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e70b34ba1ea4416adca80e4efb4e784401bb01b52b9bfcdaa3c1c59a279bd520' 
  AND token = 'N3RPms9il1nyAmKyxOwKT8T7pk5daLF2XUzEXwCoSUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}