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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e83f269bacfb619a0a409b71982b2790ca2011bd36969292cd3ef26f16463a81' 
  AND token = 'NgXF6vbGYKq80CiG4IbgQ/GCu0KuMZ5JPV2zV9EFE6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}