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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb640dd17a75c0273f6cb03ec86612c5468638efc4d2c882aac98f1b2d362077' 
  AND token = 'La4jDSbQgU8z2wqCBHuioNpmGA2T/q0+oUXSCT7TSFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}