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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f111f3241e0bc19b1cf5963963cb78a0f873697fcf20f9dc0780992e69de6e40' 
  AND token = 'EkVqbU1fd+xEqj1QfPdH6Iru9ej9Rx22PPqkmmrvUtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}