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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49ffdc2c910e23dc408275dab60f5424620bde3ee37778dfa4655358ab1b3db1' 
  AND token = 'DGd5h14uRkaB3Eud5LvydvE+Ux+oGH77VTDHTUZV/yE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}