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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '777d5d931b03f22e28f8564eddc0cff84d9a15ba269daad67af2401ff4ccc16f' 
  AND token = 'A7v0moeeDIq3zqlz30j9Y+ZjQKQjhxl5bAylAN4cC1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}