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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc6e7e15cd10a4f0cb831a1a28ee979fa015636cd082e4cd7ebd778f2859a638' 
  AND token = 'oiN35soVqdq0ajT7ssCJ7bS8HUn6F7u/LQjc6HFFwh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}