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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e78a767898bf6fdb68e390ccb17ce797000073d054e350cadb91bd1f481e074' 
  AND token = '7CX98hARfagOSJPte2whSRFJdHm4bI1g7DP7JJHCCo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}