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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8de1712f9c73544ef0fef5d9ec3933405564f6bc8e289a23c6ac97b51b0efe84' 
  AND token = 'Sf22LK8+8sXtgqpCkHd+GLQaMz+gZPlf1X114j5G6XQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}