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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43775ea793b81d0b236d47d60bd35c3e7a42be5d81e8354535a1f62a8cc4ad48' 
  AND token = '9QK9ddWMSe180eY8hViy1yuu6FDTTtW8yGWvAvEBoRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}