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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0290d080fcc76f6fd0f03c8935299dcc780138f5ac776b7d912ff7ceda83b66a' 
  AND token = 'n2TUw6+4Bl/N5wrZCwUDWTI1YIf6OC6gulK3uyAwQYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}